The goals of the laboratory revolve around the plasticity and regeneration of skeletal muscle, in efforts to mitigate the devastating functional limitations of limb salvage and traumatic muscle injuries. We examine the musculoskeletal and neuromuscular systems in efforts to understand and develop effective strategies to address the deleterious effects of complex traumatic muscle injuries, namely volumetric muscle loss. Ongoing work broadly encompasses investigating muscle and nerve interactions, metabolic and fibrotic comorbidities, regenerative rehabilitation treatment strategies, and the combination of these in more complex orthopedic injuries.

Sarah Greising, Ph.D., Lab Director